The latest medical technology and biochemistry techniques helped scientists at Factor Hair develop specialised molecules and innovative ingredients.
The active ingredient in Factor Hair — MKMS24
The unique active agent in Factor Hair ‘MKMS24’, which is formulated with Lentils, Thyme and Bamboo and is produced with sustainable biotechnology.
It tackles the problem of hair loss at the roots. It stimulates the proliferating and dermal papilla cells in the hair bulb, and encourages hair growth. Factor Hair Activator also inhibits a hair loss enzyme called 5α reductase II. This prevents hair loss in men and women and allows users to regain stronger and fuller hair.
The human hair follicle is a complex structure consisting of an outer root sheath, an inner root sheath, the hair shaft, the bulge and the sebaceous gland. The bottom part of the hair follicle is called the hair bulb. This is where Factor Hair Activator tackles the problem of hair loss.
The bottom part of the hair follicle is called the hair bulb. This is where Factor Hair Activator tackles the problem of hair loss, at the root.
The hair cycle is divided into 3 phases: Anagen, catagen and telogen.
A healthy follicle regenerates naturally and rejoins the blood connection of the scalp to form a new hair shaft. If the nutrient supply is not optimal or dihydrotestosterone (DHT) prevents reattachment, the hair thins and does not regenerate as usual.
MKMS24 thus ensures that the anagen phase, the first and longest growth phase in the hair cycle, is extended and the telogen phase, the phase in which the hair shaft dissolves and falls out, is shortened. Factor Hair Activator also provides your hair with all the nutrients it needs to fully regenerate.
Thanks to its unique formula, Factor Hair Activator can stop further hair loss and restore thinned hair to its original strength and fullness.
In a clinical study, the effect of four different plant extracts on gene expression in hair follicles was investigated. In this study MKMS24 was processed into a neutral product, which was applied to the scalp of volunteers for 3 weeks in the morning and evening. Before and after the treatment more than a dozen follicles were taken and analysed, among them 30 genes which are especially important for hair physiology.
The results showed a positive change in the gene expression of fibroblast growth factor 7 (FGF7) and noggin, as well as the genes involved in hair pigmentation. Both genes were strongly activated by MKMS24.
FGF7 and noggin proteins are signaling compounds that are important for the induction of a new hair growth phase. While Noggin inhibits the activity of bone morphogenetic protein 4 (BMP4), which plays a suppressive role in the transition of the telogen phase back to the anagen phase, FGF7 helps instruct hair nucleus cells to proliferate and initiate a new hair cycle.
The expression of FGF7 was increased by 62% and of Noggin by 89% after three weeks of treatment. FGF7 was stimulated in 8 and Noggin in 13 of a total of 15 subjects, which had a positive effect on hair growth.
In another study, 7% MKMS24 extract was processed into a neutral product and tested on a total of 17 subjects, 7 female and 10 male. The test product was applied twice a day to a defined zone on the scalp over a period of 20 weeks. Using a so-called “phototrichogram”, the treated scalp areas were photographed from close up before and after the test phase. They were then evaluated with special software to analyze hair growth and the number of hair follicles.
Two days later, the shaved area was photographed again to verify the amount of hair follicles in the growth phase (anagen hair).
The scalp areas treated with MKMS24 extract showed increased density of anagen hair (+21.7) and decreased density of telogen hair (-36.3). At the beginning of the 20-week treatment a slightly increased hair loss with about 22 telogen hairs was observed in the volunteers. At the end of the study, only about 12 telogen hairs were found in the same zone.