Thanks to the latest technologies in the field of medical technology and biochemistry, this unique active ingredient has been derivated to develop the special Factor Hair formula — a formula that delivers on its promises.
The MKMS24 molecule is derived from lentils, thyme and bamboo and is therefore 100% natural. The active substance MKMS24 stimulates hair growth directly at the root and inhibits the enzyme 5‑reductase II, which forms DHT from testosterone. DHT is the cause of one of the most common forms of hair loss, androgenetic alopecia.
The hair cyclically goes through 3 growth phases, each lasting three to five years. Of course, not all hairs go through this cycle at the same time, but each hair runs this cycle in itself time-delayed to the other hairs. This three-phase cycle repeats itself again and again. How often this happens is genetically predetermined, just like our hair length. This is a natural process and not a cause for concern. The loss of 100–200 hairs per day is considered normal and is not perceptible to the naked eye.
If the natural cycle is shortened by nutrient deficiency or the influence of the hormone dihydrotestosterone (DHT), increased to complete hair loss can occur. Often the hair loss begins creeping. First, the hair gets thinner and thinner. A sign that the hair is no longer optimally supplied with nutrients. Hair loss, with light and bald spots, is usually only noticed when it is already more advanced.
Thanks to MKMS24, this process can not only be slowed down, but even reversed.
The hair cycle is divided into 3 phases: anagen, katagen and telogen.
The anagenic phase: In the first and longest phase, the hair lengthens daily for 3–5 years.
The catalytic phase: In this phase, the hair follicle shrinks and detaches from the blood supply in the scalp and transitions into a kind of resting state. This phase lasts only a few weeks.
The telogene phase: During the transition to this last phase of hair growth, the hair follicle triggers the hair shaft and the hair fails.
A healthy follicle regenerates naturally and reconnects to the blood connection of the scalp to form a new hair shaft. If the nutrient supply is not optimal or dihydrotestosterone (DHT) prevents the reconnection, then the hair dilutes and does not regenerate as usual.
MKMS24 thus ensures that the anagen phase, the first and longest growth phase in the hair cycle, is prolonged and the telogen phase, the phase in which the hair shaft dissolves and falls out, is shortened. In addition, Factor Hair Activator optimally supplies your hair with all the nutrients it needs to fully regenerate.
Thanks to its unique formula, Factor Hair Activator allows you to stop further hair loss and restore already thinned hair to its original strength and fullness.
In a clinical study, the effect of four different plant extracts on gene expression in hair follicles was investigated. MKMS24 was processed into a neutral product in this study, which was applied to the scalp of subjects over 3 weeks, in the morning and in the evening. Before and after the treatment, more than a dozen follicles were taken and analyzed, including 30 genes that are specifically critical for hair physiology.
The results showed a positive change in gene expression of fibroblast growth factor 7 (FGF7) and noggin, as well as genes involved in hair pigmentation. Both genes were strongly activated by the MKMS24.
FGF7 and noggin proteins are signal compounds that are important for inducing a new hair growth phase. While noggin inhibits the activity of “bone morphogenetic protein 4” (BMP4), which plays an oppressive role in the transition of the telogen phase back to the anagen phase, FGF7 helps instruct the hair germ cells to multiply and initiate a new hair cycle.
The expression of FGF7 was increased by 62% after three weeks of treatment and 89% of noggin. FGF7 was stimulated in 8 and noggin in 13 out of a total of 15 subjects, which have a positive effect on hair growth.
In another study, 7% MKMS24 extract was processed into a neutral product and tested on a total of 17 subjects, 7 female and 10 males. The test product was applied twice a day for a period of 20 weeks a day to a defined zone on the scalp. Using a so-called “phototricogram”, the treated scalp areas were photographed up close before and after the test phase. They were then evaluated using special software to analyze hair growth and the number of hair follicles.
Two days later, the shaved zone was photographed again to verify the amount of hair follicles in the growth phase (anagen hair).
The scalp areas treated with the MKMS24 extract showed an increased density of anagenhair (+ 21.7) and decreased density of telogenhaar (-36.3). At the beginning of the 20-week treatment, a slightly increased hair loss with about 22 telogen hair was found in the probantes. At the end of the study, only about 12 telogen hairs were found in the same zone.